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. 2019 Jan 2;14(1):e0207785. doi: 10.1371/journal.pone.0207785

Table 9. 47 miRNAs with significant effect of time in relation to MMA fight in saliva and serum.

miRNA Time (47) Fluid (21) Interaction (20) Pattern Top Human Tissues Human CSF
miR-4529-3p 0.001048* 0.000171* 0.000260* Delayed Serum CNS
miR-4782-5p 0.001478* 0.771777 0.007645* PBMC, Tonsils
miR-4495 0.002438* 0.001105* 0.068731 Breast, Umbilicus
miR-3663-3p 0.004628* 0.393426 0.006147* CNS
miR-203a-3p 0.005004* 0.953766 0.019048* Skin, Head/Limb ++++
miR-3170 0.005494* 0.082871 0.001233* Acute Saliva Liver, Kidney +
miR-5588-5p 0.005613* 0.000210* 0.342059 Delayed Serum Liver, Lymphocyte +
miR-3677-5p 0.005844* 0.000047* 0.277949 Neurospheres
miR-4485-3p 0.006945* 0.002592* 0.006234* Germ cell, Tonsil, Nose ++
miR-6755-5p 0.007367* 0.429112 0.008562* -
miR-6855-3p 0.010420* 0.15248 0.013031* -
miR-8089 0.013930* 0.157337 0.960979 Delayed Serum - ++
miR-365a-5p 0.014130* 0.012816* 0.125236 Lymphocyte, Pigmented cell
miR-550a-3-5p 0.014394* 0.000366* 0.014623* Delayed Serum Nose, Adipose Tissue
miR-3919 0.015643* 0.000245* 0.475008 Acute Saliva CNS
miR-499a-5p 0.016956* 0.184234 0.529812 Heart, Kidney, Germ cell +
miR-433-3p 0.017808* 0.000472* 0.535641 Acute Saliva Pharynx, CNS +
miR-139-5p 0.019453* 0.000483* 0.016949* Delayed Serum Bladder, Kidney, Spleen +
miR-8082 0.021022* 0.013965* 0.027255* - ++
miR-2682-5p 0.021615* 0.000003* 0.411552 Acute Saliva CNS +
miR-548ab 0.021980* 0.891496 0.018717* Lymphocyte, Tonsil, CNS
miR-3678-3p 0.022890* 0.002552* 0.24893 Delayed Serum Lymphocyte, Tonsil
miR-4632-3p 0.024974* 0.190454 0.020774* Acute Saliva Spleen
miR-5583-5p 0.025676* 0.012704* 0.399673 Embryonic kidney +
miR-6870-3p 0.026225* 0.028773* 0.109315 Acute Saliva -
miR-1270 0.026246* 0.009370* 0.361532 Delayed Serum Lymphocyte, Tonsil, Thyroid +
miR-3664-3p 0.027180* 0.102718 0.023126* Delayed Serum Liver, Tonsil
miR-421 0.028354* 0.055815 0.014727* Delayed Serum Stem cell, Kidney ++
let-7b-3p 0.028535* 0.070946 0.839897 Acute Saliva Umbilicus, Nose
miR-4800-5p 0.029069* 0.942453 0.412773 Lymphocyte, Tonsil, Lung ++
miR-4749-5p 0.029116* 0.378594 0.885014 Lymphocyte, Tonsil
miR-30c-1-3p 0.029679* 0.529053 0.216003 Delayed Serum Heart, Nose ++
miR-616-5p 0.029836* 0.41128 0.177306 Nose, Adipose tissue
miR-135b-5p 0.031594* 0.422428 0.031404* Nose, Testes
miR-6840-5p 0.037916* 0.264125 0.274613 - +
miR-608 0.038108* 0.003982* 0.532572 Acute Saliva Breast, Spleen, Thymus +
miR-374c-5p 0.038280* 0.209441 0.412421 CNS +
miR-4760-5p 0.040453* 0.275308 0.027557* Acute Saliva Keratinocytes, CNS +
miR-4727-3p 0.042900* 0.045677* 0.189207 Delayed Serum Stem Cell, Vertebral disc
miR-501-3p 0.043792* 0.113446 0.042896* Delayed Serum Nose, Adipose tissue +
miR-3187-5p 0.043874* 0.579419 0.189533 PBMC, Tonsil
miR-3118 0.046986* 0.134052 0.028899* Acute Saliva PBMC, Tonsil Plasma Cell +
miR-766-3p 0.047390* 0.212496 0.78748 Pharynx, Tonsil, Nose +
miR-6809-3p 0.047799* 0.000051* 0.411403 Delayed Serum - +
miR-601 0.049388* 0.056646 0.113978 Acute Saliva Placenta, Cerebellar Cortex +
miR-4660 0.049499* 0.012181* 0.210414 Acute Saliva Pigment cell, Tonsil
miR-4699-5p 0.049827* 0.000083* 0.031381* Adipose tissue, Nose, Liver ++

Asterisks indicate change according to Time, Fluid or the interaction. Bold miRNAs were also changed due to HTH levels. Pattern column indicates miRNAs shown in Figs 9 & 10. Other conventions same as Table 5.