Table 10. Top biological pathways overrepresented by acute saliva response miRNAs.

KEGG pathway	FDR	Genes	miRNAs	let-7b-3p	2682-5p	3118	3170	3919	433-3p	4632-3p	4660	4760-5p	601	608	6870-3p
Prion diseases	7.0E-11	7	5	+	+	n/a	n/a	n/a	+	n/a	n/a	+	+	n/a	n/a
Long-term depression	3.4E-06	28	10	+	+	+	+	+	+	+	+	+	n/a	+	n/a
Hippo signaling pathway	7.1E-06	46	11	+	+	+	+	+	+	+	+	+	+	+	n/a
Proteoglycans in cancer	1.2E-05	60	11	+	+	+	+	+	+	n/a	+	+	+	+	+
Signaling pathways regulating pluripotency of stem cells	1.5E-05	51	11	+	+	+	+	+	+	n/a	+	+	+	+	+
Thyroid hormome signaling pathway	1.8E-05	41	11	+	+	+	+	+	+	n/a	+	+	+	+	+
N-Glycan biosynthesis	1.0E-04	15	8	+	+	+	+	+	+	n/a	+	n/a	n/a	+	+
Glutamatergic synapse	0.0008	36	11	+	+	+	+	+	+	n/a	+	+	+	+	+
Glycosaminoglycan biosynthesis—heparan sulfate/herapan	0.0009	10	8	n/a	+	+	n/a	+	n/a	n/a	+	+	+	+	+
Axon guidance	0.0019	43	10	+	+	+	+	+	+	n/a	+	+	+	+	n/a
Adherens junction	0.0019	29	6	+	+	n/a	n/a	+	+	n/a	+	+	n/a	n/a	n/a
Amphetamin addiction	0.0019	21	10	+	+	+	+	+	+	n/a	+	+	+	+	n/a
Estrogen signaling pathway	0.0019	31	11	+	+	+	+	+	+	n/a	+	+	+	+	+
Cocaine addiction	0.0035	18	10	+	+	+	+	+	+	n/a	+	+	+	+	n/a
ErbB signaling pathway	0.0036	30	9	+	+	+	n/a	+	+	n/a	+	+	+	+	n/a

Note: Conventions same as Table 8. Pathways in bold were the same or highly-related to pathways enriched in the delayed serum response miRNA targets.