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. Author manuscript; available in PMC: 2019 Jan 2.
Published in final edited form as: J Alzheimers Dis. 2016 Jul 14;53(4):1641–1652. doi: 10.3233/JAD-160365

Table 2.

Cognitive domain associations with diffuse and neuritic plaques

Diffuse Plaques
Cognitive Domain Present (n = 79) Absent (n = 44) p-value Cohen’s d
Global Cognitive Score 0.52±0.28 0.70±0.41 0.10 0.51
Episodic Memory 0.80±0.41 0.97±0.40 0.16 0.42
Semantic Memory 0.38±0.45 0.59±0.46 0.14 0.46
Working Memory 0.46±0.49 0.54±0.57 0.72 0.15
Perceptual Speed 0.52±0.55 0.76±0.65 0.35 0.40
Visuospatial 0.45±0.53 0.64±0.72 0.24 0.30

Neuritic Plaques
Cognitive Domain Present (n = 77) Absent (n = 46) p-value Cohen’s d

Global Cognitive Score 0.49±0.29 0.75±0.35 0.001 0.81
Episodic Memory 0.77±0.42 1.01±0.36 0.03 0.62
Semantic Memory 0.34±0.46 0.65±0.40 0.008 0.72
Working Memory 0.42±0.50 0.61±0.53 0.14 0.37
Perceptual Speed 0.51±0.56 0.77±0.63 0.13 0.44
Visuospatial 0.39±0.52 0.73±0.68 0.004 0.56

Diffuse and Neuritic Plaques
Cognitive Domain Present (n = 72) Absent (n = 39) p-value Cohen’s d

Global Cognitive Score 0.50±0.29 0.77±0.36 0.001 0.83
Episodic Memory 0.78±0.42 1.02±0.36 0.04 0.61
Semantic Memory 0.36±0.45 0.65±0.41 0.04 0.67
Working Memory 0.44±0.51 0.61±0.56 0.25 0.32
Perceptual Speed 0.53±0.56 0.84±0.62 0.06 0.52
Visuospatial 0.41±0.53 0.74±0.70 0.006 0.53