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. Author manuscript; available in PMC: 2019 Jan 2.
Published in final edited form as: Biochemistry. 2016 Feb 9;55(7):1149–1158. doi: 10.1021/acs.biochem.5b01280

Figure 1.

Figure 1.

Dynamic O-GlcNAcylation of the Pol II CTD. (A) The Pol II CTD consists of 52 imperfect heptad repeats of YSPTSPS, which can be dynamically O-GlcNAcylated (circled G). (B) Illustration showing that O-GlcNAcylation is catalyzed by OGT and removed by OGA.