Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Jan 2;10:4. doi: 10.1038/s41467-018-07885-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Chromosome-Y assembly overview and comparisons. a Dot-plot comparing the resolved MSY of GRCh38 with HG02982. The reconstruction is highly continuous along most sequence classes, with ampliconic regions showing a higher degree of fragmentation. Seg. Dup. (intra) refers to intra-chromosomal segmental duplications, Seg. Dup. (inter) refers to inter-chromosomal segmental duplications. Altogether, ~ 50% of the of the Y chromosomes resolved sequence space in GRCh38—> 13 Mb—are annotated as segmental duplications. b Treemap comparing the contiguity of HG02982 chrY with GRCh38 chrY and the gorilla Y chromosome by Tomaszkiewicz et al. The size of each rectangle corresponds to the size of a contig within each of the assemblies. Neighboring rectangles are colored differently as a visual aid. c Repeat landscape of common, interspersed repeats annotated equally in GRCh38 and HG02982. Common repeats—including very recent ones—are well resolved in HG02982. The exception are satellite sequences, and a population of somewhat divergent (~ 20%) LTR elements, which are absent in HG02982 (see supplementary Figures 7-9). Source data are provided as a Source Data file