Table 2.
The methylation of ZNF132 gene and control gene in ESCC
Gene name | Mean (case) | Mean (control) | P valuea | P valueb | Sensitivity | Specificity | Area Under the curve (AUC) |
---|---|---|---|---|---|---|---|
ZNF132 | 0.36 | 0.11 | 2.2 × 10−16 | 2.2 × 10−16 | 70.8% | 80.6% | 0.82 |
LINE-1 | 0.55 | 0.73 | 2.16 × 10−8 | ||||
ChrM | 0.03 | 0.02 | 2.59 × 10−1 |
aP value is calculated through the Wilcoxon's rank-sum test followed by FDR (false discovery rate) adjustment for multiple correction
bP value determined by logistic regression