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. 2018 Dec 18;10(1):4. doi: 10.1038/s41419-018-1207-4

Fig. 6. E2 promoted cell proliferation, migration, invasion, and anti-apoptosis by upregulating miR-200c.

Fig. 6

a CCK-8 assay showing cell proliferation in RL-952 cells that were transfected with miR-200c mimics or inhibitor combine with E2-induced for 48 h. b, c Flow cytometry analysis showed cell cycle in RL-952 cells that were transfected with miR-200c mimics or inhibitor combine with E2-induced for 48 h. d, e FACS analysis showing apoptosis in RL-952 cells that were transfected with miR-200c mimics or inhibitor combine with E2-induced for 48 h. f, g Migration and invasion assay in RL-952 EEC cells that were transfected with the miR-200c mimics or inhibitor combine with E2-induced for 24 h. Cells were evaluated at 16 h after transfection (×200 magnification). The results are shown as the mean ± SEM from three independent experiments (*P < 0.05, **P < 0.01)