Table 5. Summary of Initial and Recent Clinical Study Showing Response Rate.

	Type	Numbers	Child-Pugh	BCLC	Microsphere (µm)	Criteria	Response Rate	Region
Varela et al. 2007 (1)	P	27	A	B	Beads	RECIST, EASL	6 m: OR 44.4% RECIST OR 66.6% EASL	Spain
					500–700
Poon et al. 2007 (46)	P	35	A	A, B	Beads	RECIST, mRECIST	1 m: OR 50% RECIST OR 70% mRECIST	China
					500–700		4 m: OR 35.7% RECIST OR 42.9% mRECIST
Grosso et al. 2008 (47)	P	50	A, B	N/A	Microspheres	EASL	1 m: OR 84%	Italy
					50–100
Kalva et al. 2011 (48)	R	54	A, B, C	N/A	Beads	RECIST	1 m: OR 14.8%	USA
					300–500
Manini et al. 2015 (49)	P	55	A, B	A	Beads	mRECIST	1 m: OR 84%	USA
					100–300
Yu et al. 2016 (28)	R	60	N/A	N/A	Beads	mRECIST	1m: OR 73.3%	Taiwan
					100–300
					300–500
Lee et al. 2017 (20)	P	152	A, B	A, B, C	Beads	mRECIST 300–500	1 m: OR 91%	Korea
					100–300		6 m: OR 55.4%
					300–500
Sandow et al. 2018 (50)	R	93	A, B, C	A	Beads	mRECIST	Initial 1 m: OR 76%	USA
					100–300		Final (before transplant mean 179 days): OR 82%

EASL = European Association for Study of Liver, mRECIST = modified Response Evaluation Criteria in Solid Tumors, N/A = non-applicable, OR = objective response, P = prospective, R = retrospective, RECIST = Response Evaluation Criteria in Solid Tumors