Fig. 1. Effects of SPA0355 on body weight and uterine weight of OVX mice.

OVX mice were treated with vehicle or SPA0355 (10 or 50 mg/kg, i.p.) for five weeks. At the end of the study, body weight (A) and uterine weight (B) were measured. Values are the mean±SEM (n=5). ^**p<0.01 vs. sham-operated mice. SPA, SPA0355.