Table 2.

Median of pairwise genetic and amino acid distance calculated for all available PCV-1, PCV-2, and PCV-3 sequences.

		Complete genome			Cap			Rep
		PCV-1	PCV-2	PCV-3	PCV-1	PCV-2	PCV-3	PCV-1	PCV-2	PCV-3
DNA	PCV-1	0.011 [0.000–0.026]	0.228 [0.220–0.271]	0.533 [0.528–0.543]	0.017 [0.000–0.043]	0.332 [0.314–0.352]	0.598 [0.586–0.611]	0.006 [0.000–0.070]	0.174 [0.116–0.194]	0.500 [0.491–0.527]
	PCV-2	0.228 [0.220–0.271]	0.037 [0.001–0.102]	0.525 [0.518–0.544]	0.332 [0.314–0.352]	0.057 [0.000–0.172]	0.547 [0.539–0.569]	0.174 [0.116–0.194]	0.022 [0.000–0.056]	0.495 [0.485–0.520]
	PCV-3	0.533 [0.528–0.543]	0.525 [0.518–0.544]	0.009 [0.000–0.024]	0.598 [0.586–0.611]	0.547 [0.539–0.569]	0.014 [0.000–0.028]	0.500 [0.491–0.527]	0.495 [0.485–0.520]	0.006 [0.000–0.034]
Amino acid	PCV-1	NA	NA	NA	0.028 [0.000–0.071]	0.303 [0.283–0.346]	0.748 [0.732–0.760]	0.006 [0.000–0.075]	0.147 [0.088–0.194]	0.583 [0.577–0.607]
	PCV-2	NA	NA	NA	0.303 [0.283–0.346]	0.055 [0.000–0.177]	0.689 [0.681–0.736]	0.147 [0.088–0.194]	0.009 [0.000–0.075]	0.574 [0.564–0.602]
	PCV-3	NA	NA	NA	0.748 [0.732–0.760]	0.689 [0.681–0.736]	0.012 [0.000–0.035]	0.583 [0.577–0.607]	0.574 [0.564–0.602]	0.003 [0.000–0.031]

The distance range is reported between brackets after removal of the lower and upper 0.1 percentile. This measure was selected to exclude extreme values, which could be due to poor quality of some sequences challenging to be detected during alignment inspection. NA, non-applicable.