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. 2018 Nov 12;38(1):e99576. doi: 10.15252/embj.201899576

Figure 5. Metabolomics analysis of HSA‐Cre muscles.

Figure 5

  1. Metabolomics profile of GC muscle of 4‐month‐old HSA‐Cre (n = 7) and control (n = 4) mice presented as heatmap visualization and hierarchical clustering analysis of compounds with P ≤ 0.05, Student's t‐test (see Materials and Methods for details). Rows: metabolites; columns: samples; color key indicates metabolite expression value (blue: lowest; red: highest).
  2. Fold change of phospholipid precursors in GC muscles of 4‐month‐old HSA‐Cre (n = 7) and control (n = 4) mice measured by liquid chromatography (LC) tandem mass spectrometry (MS/MS) (*P < 0.05).
  3. Fold change of Lactate/Pyruvate, Pyruvate/Acetyl‐CoA, Pyruvate/Citrate, ATP/AMP, and ATP/ADP ratios in GC muscles of 4‐month‐old HSA‐Cre (n = 7) and control (n = 4) mice (*P < 0.05).
Data information: Two‐tailed Student's t‐test was used for statistical analysis. Data are expressed as means ± SEM.