Figure 1.

Experimental design and macroscopic characterization of the experimental groups. (A) Sex-matched mice were divided into four groups based on their genotype (Wild Type or Winnie) and their diet (enriched with Control or Bronze lyophilized tomato fruit). Mouse weight was recorded at the beginning of diet administration (Day 0) and at the end of the trial (2 Weeks). Fecal samples were collected for microbial meta-analyses at both time points (Day 0 and Week 2). Tissues were explanted and analyzed at the end of the treatments as indicated. Analysis of mice from different groups included: mouse weight (B), colon weight/mouse weight (C) and colon length/mouse weight (D). Black bars show the values at Day 0, striped bars show the Control- and white bars the Bronze-enriched diet. Statistical evaluation was performed using unpaired two-tailed Student’s t-tests.