Table 1.

Effects of shear and ultrasonic times on the size, size distribution, and LC loading capacity of LC/PLA nanoparticles ^a.

Entry	Shear Time (min)	Ultrasonic Time (min)	Mean Diameter (nm)	PDI	LC Loading Capacity (%)
1	5	10	270.33 ± 5.13	0.17 ± 0.02	45.08
2	10	10	196.93 ± 2.66	0.16 ± 0.015	46.6
3	10	15	190.52 ± 3.74	0.10 ± 0.019	49.4
4	15	10	205 ± 1.39	0.11 ± 0.023	48.21

^a PVA concentration was 2%, water–oil ratio was 4:3, PLA concentration was 133 g/L, and LC-PLA ratio was 1:1.