Cytotoxicity assay: representation of ARPE-19 cell viability in presence of PUFA quercetin derivatives; natural quercetin (quer), quer-3-LA (13), quer-3-ALA (14), quer-3-DHA (15) and quer-7-ALA (18) expressed as percentage of viability in function of drug concentration introduced on cells. Results are expressed in mean ± SD and are from at least n = 3 independent experiments. Results are normalized with 100% viability for non-treated control cells. Student’s t-test or Mann-Whitney’s test, * p < 0.05, ** p < 0.01, *** p < 0.001, versus natural quercetin (quer) at equivalent concentration.