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. 2018 Nov 23;9(12):571. doi: 10.3390/genes9120571

Table 1.

Summary of aptamers utilised in DNA origami research.

Name Target Sequences Length/DNA or RNA Employed by Ref.
HD1 Thrombin (exosite I) GGTTGGTGTGGTTGG 15nt ssDNA [53,54,59,61] [3]
HD22 Thrombin (exosite II) AGTCCGTGGTAGGGCAGGTTGGGGTGACT 29nt ssDNA [18,56,59,63] [52]
NU172 1 Thrombin CGCCTAGGTTGGGTAGGGTGGTGGCG 26nt ssDNA [56] [55]
36t PDGF (platelet derived growth factor) CACAGGCTACGGCACGTAGAGCATCACCATGATCCTGTGT 40nt ssDNA [18] [51]
41t PDGF TACTCAGGGCACTGCAAGCAATTGTGGTCCCAATGGGCTGAGTAT 45nt ssDNA [70,71,72] [51]
SL12 VEGF (vascular endothelial growth factor) ATACCAGTCTATTCAATTGGGCCCGTCCGTATGGTGGGTGTGCT 3 44nt ssDNA [72] [73]
TE17 CCRF-CEM cell CAGCTACGCAATACAAAACTCCGAACACCTGCTTCTGACTGGGTGCTG 48nt ssDNA [70] [74]
sgc8c PTK7 ATCTAACTGCTGCGCCGCCGGGAAAATACTGTACGGTTAGA 41nt ssDNA [70] [75,76]
2008s PfLDH CTGGGCGGTAGAACCATAGTGACCCAGCCGTCTAC 35nt ssDNA [57,77] [60]
AFB1 aptamer AFB1 GTTGGGCACGTGTTGTCTCTCTGTGTCTCGTGCCCTTCGCTAGGCCCAC 49nt ssDNA [58] [62]
ATP aptamer ATP ACCTGGGGGAGTATTGCGGAGGAAGGT 4 27nt ssDNA [78,79,80] [81,82]
ATP aptamer ATP 1: CTAcUACCTGGGGGAGTAT 5
2: TGCGGAGGAAGGTcUAG		 43nt ssDNA [83] [84]
aptakiss and GTP switch GTP aptakiss: UGCUCGGCCCCGCGAGCA
GTPswitch: UCCGAAGUGGUUGGGCUGGGGCGUGUGAAAACGGAGTPswitch mutant: UCCGAAGUGGUUGGGCUGGGCGUGUGAAAACGGA		 18nt RNA/35nt RNA/34nt RNA [85] [86]
S2.2 MUC-1 GCAGTTGATCCTTTGGATACCCTGG 25nt ssDNA [87,88] [89]
cocaine aptamer cocaine GGGAGACAAGGATAAATCCTTCAATGAAGTGGGTCTCCC 6 39nt ssDNA [79,80] [90]
AS1411 2 Nucleolin GGTGGTGGTGGTTGTGGTGGTGGTGG 26nt ssDNA [91] [92,93]
C2NP CD30 ACTGGGCGAAACAAGTCTATTGACTATGAGC 32nt ssDNA [94] [95]
zif268 binding site zif268 CTGCGTGGGCGTGTTTTCACGCCCACGCAG 30nt ssDNA [64,66,69] [66]
AZP4 binding site AZP4 CTTACGTGGCATGTTTCATGCCTCGTAAG 29nt ssDNA [66,69] [66]
GCN4 binding site GCN4 CTTCATGAGTCATGCGTTTTCGCATGACTCATGAAG 36nt ssDNA [64,67] [67]

1 Also known as ARC2172. 2 Also known as AGRO100. 3 Derivative of VEa5 [96]. 4 In [78,80] a single G at 3′ end was added as a result of optimisation. 5 Split aptamer. cU in the sequences are dye modified nucleosides. 6 Derivative of MNS-4.1 [97]. AFB1: aflatoxin B1.