Inflammatory mediator status pre- and post-MSCs coculture. (a) Levels of elevated TNF-α, IL-1β, and IL-12 during stress and rescued post-MSCs coculture. (b) Anti-inflammatory TFG-β, IL-6, and IL-10 cytokine status during stress and post-MSCs coculture. (c) Left panel shows Western blot of NF-κB, COX-2, and β-actin expression. Right panel is blot-band quantification using Image J densitometry. Relative protein expression of NF-κB and COX-2 of the stressed group are compared with the control and rescue groups. Bar represents mean ± SEM, * p < 0.05, ** p < 0.01, *** p < 0.001; significant; n = 3.