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. 2018 Dec 4;10(12):515. doi: 10.3390/toxins10120515

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Binding and interaction modes of antitoxins and toxins.; (a,b) Structural views of binding between protein antitoxins and protein toxins. (a) The antitoxin VapB26 (red) and toxin VapC26 (blue) from Mycobacterium tuberculosis interact in a 1:1 ratio (PDB code 5X3T).; (b) The antitoxin MazE4 (red) and toxin MazF4 (blue and light blue) from M. tuberculosis interact in a 1:2 ratio (PDB code 5XE3); (c,d) Structural views of binding between RNA antitoxins and protein toxins; (c) The antitoxin ToxI (red) and toxin ToxN (blue colors) from Pectobacterium atrosepticum interact in a 1:1 ratio (PDB code 2XDD); (d) The antitoxin CptI (red) and toxin CptN (blue colors) from Eubacterium rectal interact in a 1:1 ratio (PDB code 4RMO).