Table 1.
Comparison of demographic and clinical features of NCGS versus non-gluten-related microscopic enteritis patients (univariate analysis).
| Non Gluten-Related Microscopic Enteritis (n = 41) |
NCGS (n = 22) |
p Value | |
|---|---|---|---|
| Age (mean ± standard deviation) | 36.0 ± 13.3 | 30.6 ± 8.7 | 0.09 |
| Female sex, n (%) | 31 (75.6) | 19 (86.4) | 0.51 |
Marsh classification
|
24 (58.5) 17 (41.5) |
7 (31.8) 15 (68.2) |
0.07 |
| AGA, n (%) | 1 (2.5) | 6 (27.3) | 0.006 |
| ANA, n (%) | 5 (12.2) | 10 (45.4) | 0.005 |
| Familiarity for celiac disease, n (%) | 0 (0) | 2 (9.1) | 0.12 |
| Autoimmune thyroiditis, n (%) | 6 (14.6) | 9 (40.1) | 0.03 |
| Other autoimmune diseases, n (%) | 2 (4.9) | 2 (9.1) | 0.61 |
| Anemia, n (%) | 7 (17.1) | 3 (13.6) | 0.70 |
| Folate deficit, n (%) | 6 (14.6) | 7 (31.8) | 0.19 |
HLA, n (%)
|
24 (58.5) 17 (41.5) |
21 (95.4) 1 (4.6) |
0.002 |
| Weight loss, n (%) | 8 (19.5) | 10 (45.4) | 0.04 |
| Bloating, n (%) | 22 (53.6) | 17 (77.3) | 0.10 |
| Diarrhea, n (%) | 7 (17.1) | 9 (40.1) | 0.08 |
| Tiredness, n (%) | 7 (17.1) | 8 (36.4) | 0.12 |
| Headache, n (%) | 0 (0) | 11 (50) | <0.001 |
AGA: anti-gliadin antibodies; ANA: anti-nucleus antibodies; HLA: human leukocyte antigen.