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. 2018 Dec 5;7(12):245. doi: 10.3390/cells7120245

Table 7.

Top ranked two LRRK2 KO/KI experiments in “Single Gene Perturbations from GEO down”.

Name Overlap p-Value Adjusted p-Value
LRRK2 Gly2019Ser (G2019S) mutation knockin human GSE36321 sample 1688 24/265 8.38 × 1017 9.78 × 1016
LRRK2 dominant negative mutation-G2019S heterozygous human GSE33298 sample 1739 9/282 1.61 × 103 3.56 × 103