Figure 4.
Repair and reconstruction of different natural bone grafts implanted in different sites in the rabbit bone defect model. Self repair, defect repair without any scaffold. MSCs, mesenchymal stem cells. −CaP, decellularized bone scaffold without calcium phosphate. +CaP, decellularized bone scaffold with calcium phosphate. DBM, demineralized bone matrix. PDO, polydioxanone. DBM/MSCs++, a combination of DBM and MSCs infected with adenovirus-mediated-bone morphogenetic protein (Ad-BMP-2) and transforming growth factor-β3 (Ad-TGF-β3). Reproduced with permission from [92]. Copyright Elsevier Inc, 2017. Reproduced with permission from [41]. Copyright Wang et al., 2014. Reproduced with permission from [93]. Copyright Elsevier B.V., 2009.