Table 5.

Summary of the co-differential genes selected by the GMvNMF method.

Gene ID	Gene ED	Related Go Annotations	Related Diseases	Relevance Score
672	BRCA1	RNA binding and ligase activity	Breast-Ovarian Cancer, Familial 1 and Pancreatic Cancer 4	173.12
675	BRCA2	protease binding and histone acetyltransferase activity	Fanconi Anemia, Complementation Group D1 and Breast Cancer	135.87
1956	EGFR	identical protein binding and protein kinase activity	Inflammatory Skin and Bowel Disease, Neonatal, 2 and Lung Cancer	104.16
3569	IL6	signaling receptor binding and growth factor activity	Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile	58.74
4318	MMP9	identical protein binding and metalloendopeptidase activity	Metaphyseal Anadysplasia 2 and Metaphyseal Anadysplasia	45.57
1495	CTNNA1	actin filament binding	Macular Dystrophy, Patterned, 2 and Butterfly-Shaped Pigment Dystrophy	41.99
1950	EGF	calcium ion binding and epidermal growth factor receptor binding	Hypomagnesemia 4, Renal and Familial Primary Hypomagnesemia with Normocalciuria and Normocalcemia	40.84
5594	MAPK1	transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity	Chromosome 22Q11.2 Deletion Syndrome, Distal and Pertussis	39.23
2475	MTOR	transferase activity, transferring phosphorus-containing groups and protein serine/threonine kinase activity	Focal Cortical Dysplasia, Type II and Smith-Kingsmore Syndrome	34.07
887	CCKBR	G-protein coupled receptor activity and 1-phosphatidylinositol-3-kinase regulator activity	Panic Disorder and Anxiety	23.43

Note: Gene ID represents the number of the gene. Gene ED represents the gene name.