Table 3.

Notable clinical studies and meta-analyses of anti-inflammatory therapies in PCI/ coronary artery bypass grafting (CABG).

Trial/Meta-Analysis	Intervention	Design	Outcome
STICS	Rosuvastatin in elective cardiac surgery	Double blinded RCT with a placebo as control; n = 1922	Rosuvastatin did reduce CRP but did not significantly affect post-operative outcomes
CEREA-DES	Prednisone with bare metal stents in PCI	Single blinded RCT with drug eluting stents and bare metal stents without prednisone as other treatments; n = 375	Bare metal stents with prednisone and drug eluting stents both have higher event free survival compared to bare metal stents only
Meta-analysis of corticosteroids in cardiac surgery	High dose prophylactic steroids administered in on-pump CABG	54 RCTS included of variable quality; total n = 3615	No significant clinical benefits with corticosteroids