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. 2018 Nov 28;16(12):475. doi: 10.3390/md16120475

Figure 7.

Figure 7

Comparison of the steady-state inactivation kinetics of CaV3.2 before (black) and after (red) the addition of 0.6 µM of 2 and 3. Steps lasting 1 s were given directly from −110 mV to the indicated voltages in 5-mV increments, followed by 60-ms test pulses to −20 mV. (A) Normalized I/Imax under conditioning steps from −110 mV to −40 mV (n = 5), along with representative elicited ICa under potentials from −95 mV to −60 mV before (black) and after (red) the addition of 0.6 µM of 3. Error bars represent the SEM. (B) Normalized I/Imax under conditioning steps from −110 mV to −40 mV (n = 4), along with representative elicited ICa under potentials from −95 mV to −60 mV before (black) and after (red) the addition of 0.6 µM of 2. Error bars represent the SEM.