Table 1.
Annotation of the nuclear cyclophilins.
| Gene Name | UniProt Accession No. | # aa | Domain 1 | Boundary | Domain 2 | Boundary | Cryo-EM Structures |
|---|---|---|---|---|---|---|---|
| PPIA | P62937 | 165 | PPI | 1–165 | - | - | - |
| PPIE | Q9UNP9 | 301 | RRM | 7–80 | PPI | 143–299 | 5MQF, 5YZG, 5Z56, 5Z57 |
| PPIG | Q13427 | 754 | PPI | 11–176 | SR/RS repeats | 540–639 | 5YZG |
| PPIH | O43447 | 177 | PPI | 1–177 | - | - | 5O9Z |
| PPIL1 | Q9Y3C6 | 166 | PPI | 1–166 | - | - | 5MQF, 5XJC, 5YZG, 5Z56, 5Z57, 6FF4 |
| PPIL2 | Q13356 | 527 | U-BOX | 42–101 | PPI | 281–433 | - |
| PPIL3 | Q9H2H8 | 161 | PPI | 1–161 | - | - | |
| PPWD1 | Q96BP3 | 646 | WD40 | 80–453 | PPI | 490–645 | 5YZG |
| CWC27 | Q6UX04 | 472 | PPI | 14–166 | coiled-coil | 306–351 | 5Z56, 5Z58, 6FF4 |
# aa: Number of amino acids in the expressed, full-length protein. Domains are annotated as classified by SCOP and UniProtKB [37]. Domain boundaries are numbered according to amino acid residues.