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. 2018 Dec 6;7(12):184. doi: 10.3390/antiox7120184

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Attenuation with ethanolic mint extracts of 7-ketocholesterol (7KC)-induced cell growth inhibition. The effects of Mentha extracts were evaluated on 7KC (20 µg/mL (50 µM); 24 h and 48 h)-treated RAW 264.7 cells with the crystal violet test, which allows the quantification of adherent cells. After 24 h of culture, mint extracts and 7KC were simultaneously added to the culture medium. Ethanol 0.1% (used as vehicle) corresponds to the highest ethanol concentration used to dissolve 7KC. Data are mean ± Standard Deviation (SD) from two independent experiments conducted in triplicate. * Significant difference between vehicle and 7KC (Mann Whitney; p < 0.05). # Significant difference between 7KC and (7KC+ethanolic mint extract) (Mann Whitney; p < 0.05).