Table 3.
Outcomes | β | 95% CI | p |
---|---|---|---|
Composite inflammatory index a | 0.002 | −0.005; 0.009 | 0.550 |
IGF-1 (nmol L−1) b | 0.000 | −0.001; 0.000 | 0.238 |
BDNF (ng mL−1) b | 0.000 | −0.001; 0.001 | 0.799 |
VEGF (pg mL−1) b | −0.001 | −0.003; 0.002 | 0.687 |
az-score; a Composite inflammatory index calculated as sum of individual z-scores of pro-inflammatory markers (hs-CRP, IL-6, IL-8 and TNF-alpha) minus anti-inflammatory markers (IL-10 and adiponectin); b log transformed values; β represent unstandardized beta-coefficients. Results were adjusted for age, sex, BMI, habitual physical activity (kJ weekly spent in vigorous activity), genotypes for APOE (carriers of ɛ4/non-carriers) and history of CVD (yes/no).