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. 2018 Nov 22;10(12):465. doi: 10.3390/cancers10120465

Figure 1.

Figure 1

H&E (AC) and Azan (D) staining of liver sections from 52-week-old TSOD mice and H&E (EG) and Masson trichrome (H) staining of livers in a 48-week-old mouse fed CDAHFD. In the TSOD mice livers, mild fatty change and ballooning (A,B), mild inflammation (C) and Zone 3 perisinusoidal fibrosis (D) were detected. Fatty change, lipogranuloma (E,F), severe inflammation (G) and severe fibrosis (H) were obvious in CDAHFD-fed C56Bl/6J mice. Scale bar: 25 μm (B,C,F,G), 50 μm (A,D,E,H).