Figure 1.

Schematic of pharmaceutical elements of our proposal, many intermediate steps are not depicted. The text gives specifics of how ciprofloxacin and 5-FU might increase 5-ALA uptake and PpIX synthesis inside GB(glioblastoma) cells and explains how deferiprone inhibits loss of PpIX by inhibiting its conversion into heme and efflux inhibition by febuxostat.