Table 1.
Cell Line | Laser (nM) | Bandpass Filter (nm) | Fluorescence Intensity (a.u. mean ± SD) a | Relative Fluorescence Increase b | |
---|---|---|---|---|---|
Control | PD173074 | ||||
NCI-H1703 | 405 | 450/40 | 7.99 ± 0.08 | 4129.54 ± 43.02 | 516.8 *** |
NCI-H520 | 405 | 450/40 | 11.34 ± 0.10 | 6210.24 ± 191.27 | 547.6 *** |
a Cells were exposed to 10 µM PD173074 for 1 h. Fluorescence intensity was analyzed by flow cytometry; b Fluorescence increase of drug-treated cells is shown relative to untreated controls; *** p < 0.001; student’s t-test. a.u., arbitrary units.