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(A) Diagram of the major morphogenic events during islet development. (B) A cascade of different transcription factors, hormones and cell specific markers are expressed within different stages of pancreatic development that are responsible for the morphogenic events leading to islet formation and cellular differentiation. The diagram was inspired by [6,13]. DP, Dorsal pancreatic bud; VP, Ventral pancreatic bud; GB, Gall bladder; dpc, days post conception; CS, Cambridge stage.
