Table 2.

Top canonical pathways significantly enriched between treated and non-treated Fayoumis at 10 dpi. Activated pathways are Z-score > 0 and inhibited pathways are Z-score < 0. NA designates pathways without a predicted activity score.

Canonical Pathway	Z-Score
ERK/MAPK Signaling	−2.24
Thrombin Signaling	−2.24
mTOR Signaling	−2.00
Fcy Receptor-mediated Phagocytosis in Macrophages and Monocytes	−2.00
p70S6K Signaling	−1.89
B Cell Receptor Signaling	−1.89
Colorectal Cancer Metastasis Signaling	−1.89
Mouse Embryonic Stem Cell Pluripotency	−1.63
Rac Signaling	−1.34
Ga12/13 Signaling	−1.34
IL-8 Signaling	−1.34
NF-kappaB Signaling	−1.34
Regulation of eIF4 and p70S6K Signaling	−1.34
NGF Signaling	−1.34
Telomerase Signaling	−1.34
Acute Myeloid Leukemia Signaling	−1.34
Fc Epsilon RI Signaling	−1.00
fMLP Signaling in Neutrophils	−1.00
ErbB Signaling	−1.00
Growth Hormone Signaling	−1.00
EIF2 Signaling	−1.00
FLT3 Signaling in Hematopoietic Progenitor Cells	−1.00
Melanocyte Development and Pigmentation Signaling	−1.00
Renal Cell Carcinoma Signaling	−1.00
Neuregulin Signaling	−1.00
Insulin Receptor Signaling	−1.00
GM-CSF Signaling	−1.00
Sirtuin Signaling Pathway	−0.45
Prolactin Signaling	0.00
PTEN Signaling	0.00
Neuroinflammation Signaling Pathway	0.45
AMPK Signaling	NA
G Beta Gamma Signaling	NA
FcyRIIB Signaling in B Lymphocytes	NA
Renin-Angiotensin Signaling	NA
Role of NFAT in Cardiac Hypertrophy	NA
eNOS Signaling	NA
Huntington’s Disease Signaling	NA
GP6 Signaling Pathway	NA
ErbB4 Signaling	NA
Lymphotoxin B Receptor Signaling	NA
PAK Signaling	NA
CD40 Signaling	NA
Production of Nitric Oxide and Reactive Oxygen Species in Macrophages	NA
alpha-Adrenergic Signaling	NA
P2Y Purigenic Receptor Signaling Pathway	NA
Amyotrophic Lateral Sclerosis Signaling	NA