Table 1.
Treatment options for alcohol-mediated tissue/organ damage.
| Treatment Type | Effects on HIF-1α | Source |
|---|---|---|
| Antioxidants | ||
| M30 | Decreased HIF-1α | Xiao et al. Oxid Med Cell Longev, 2015. |
| Resveratrol | Decreased HIF-1α | Ma et al. PLoS One, 2017. |
| Vitamin C | Decreased HIF-1α | Guo et al. Acta Biochimica et Biophysica Sinic, 2013. |
| MitoQ | Decreased HIF-1α | Chacko et al. Hepatology, 2011. |
| Pre-endurance Training | Decreased HIF-1α | Ma et al. Hepatol Int, 2014. |
| microRNAs | ||
| miR-122 | Decreased HIF-1α | Satishchandran et al. Gastroenterology, 2018. |
| Probiotics | ||
| Lactobacillus rhamnosus GG | Increased HIF-1α | Wang et al. The American Journal of Pathology, 2012. |
| Pharmacological Treatments | ||
| Tiocetam | Increased HIF-1α | Belnichev et al. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology,2016. |
| Cerebrocurin | Increased HIF-1α | Belnichev et al. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology,2016. |
| Emodin | Increased HIF-1α | Yon et al. Birth Defects Res B Dev Reprod Toxicol, 2013. |
| Ligustrazine | Decreased HIF-1α | Lu et al. Toxicol Sci, 2017. |
| PX-478 | Decreased HIF-1α | Yun et al. Free radical biology & Medicine, 2014. |
| Methoxyestradiol | Decreased HIF-1α | Wang et al. Free Radic Biol Med, 2013. |