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. 2018 Dec 7;8(12):1022. doi: 10.3390/nano8121022

Table 6.

Predicted steady-state plasma concentration Css of the PF after the application of each formulation on 100 cm2 of skin. Therapeutic plasma concentration: 4.89 ± 1.29 µg/mL and 10.19 ± 2.43 µg/mL for young and elderly subjects, respectively. Data are represented as median (min-max).

Formulation Young Subject
Css (µg/mL) × 103 		Elderly Subject
Css (µg/mL) × 103
NLCs-F3 8.60 (7.30–11.80) 16.36 (13.75–22.25)
NLCs-F3-L 1.06 (0.99–1.14) 1.99 (1.85–2.15)
NLCs-F9 1.08 (1.07–1.09) 2.04 (2.03–2.05)
NLCs-F9-L 1.32 (1.21–1.62) 2.49 (2.28–3.06)