Fatty Acid | Severe AD | DLB | p-Value | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Name | Lipid No. | RT | Mass | Mean ± SD | Q1 | Median | Q3 | Mean ± SD | Q1 | Median | Q3 | KW | FDR |
Docosahexanoic Acid | C22:6Δ4,7,10,13,16,19 | 45.01 | 342.51 | 27.694 ± 9.311 | 20.090 | 26.970 | 34.740 | 32.329 ± 9.102 | 26.010 | 31.960 | 36.140 | 0.0328 | 0.0525 |
Nervonic Acid | C24:1Δ15 | 40.68 | 380.65 | 4.352 ± 2.385 | 2.747 | 4.633 | 5.775 | 5.348 ± 2.763 | 4.417 | 5.547 | 6.530 | DLB | 0.0251 |
Lignoceric Acid | C24:0 | 39.55 | 382.66 | 0.942 ± 0.442 | 0.576 | 0.924 | 1.125 | 1.023 ± 2.384 | 0.846 | 0.990 | 1.243 | 0.0009 | 0.0027 |
cis -13,16-Docosadienoic acid | C22:2Δ13,16 | 38.89 | 350.58 | 0.116 ± 0.059 | 0.084 | 0.102 | 0.140 | 0.144 ± 0.049 | 0.114 | 0.129 | 0.161 | 0.0014 | 0.0034 |
Arachidonic acid | C20:4Δ5,8,11,14 | 38.08 | 318.49 | 10.83 ± 4.169 | 7.929 | 10.660 | 13.790 | 14.43 ± 5.755 | 12.040 | 14.930 | 16.070 | 0.0008 | 0.0027 |
Tricosanoic Acid | C23:0 | 37.42 | 368.64 | 0.219 ± 0.154 | 0.139 | 0.209 | 0.336 | 0.238 ± 3.177 | 0.011 | 0.292 | 0.391 | 0.5651 | 0.5651 |
cis -11,14,17-Eicosatrienoic acid | C20:3Δ11,14,17 | 28.93 | 320.51 | 0.684 ± 0.508 | 0.299 | 0.527 | 1.008 | 1.105 ± 7.267 | 0.942 | 1.042 | 1.267 | 0.0001 | 0.0006 |
Erucic acid | C22:1Δ13 | 35.60 | 352.59 | 0.421 ± 0.217 | 0.276 | 0.429 | 0.559 | 0.633 ± 5.170 | 0.517 | 0.636 | 0.707 | 0.0001 | 0.0006 |
cis -8,11,14-eicosatreinoic acid | C20:3Δ8,11,14 | 37.05 | 320.51 | 1.193 ± 0.371 | 0.990 | 1.227 | 1.419 | 1.211 ± 4.636 | 0.969 | 1.176 | 1.531 | 0.0535 | 0.0755 |
Behenic acid | C22:0 | 35.18 | 354.61 | 0.202 ± 0.098 | 0.142 | 0.207 | 0.266 | 0.258 ± 8.088 | 0.213 | 0.255 | 0.325 | 0.0001 | 0.0006 |
cis -11,14-eicosadienoic acid | C20:2 Δ11,14 | 35.18 | 308.50 | 0.687 ± 0.629 | 0.222 | 0.429 | 1.083 | 0.856 ± 9.508 | 0.435 | 0.859 | 1.369 | 0.2064 | 0.2431 |
Heneicosanoic acid | C21:0 | 34.39 | 340.58 | 0.021 ± 0.008 | 0.015 | 0.021 | 0.026 | 0.023 ± 8.009 | 0.017 | 0.024 | 0.028 | 0.0312 | 0.0525 |
Linolenic acid | C18:3Δ9,12,15 | 34.20 | 294.26 | 3.954 ± 1.650 | 2.722 | 3.979 | 4.928 | 5.195 ± 9.834 | 4.679 | 5.519 | 5.528 | 0.0001 | 0.0006 |
cis -11-Eicosanoic acid | C20:1 Δ11 | 33.45 | 310.50 | 1.842 ± 1.316 | 0.377 | 1.975 | 2.640 | 2.137 ± 2.357 | 1.123 | 2.669 | 2.845 | 0.1439 | 0.1919 |
Arachidic acid | C20:0 | 32.85 | 326.56 | 0.224 ± 0.079 | 0.169 | 0.239 | 0.266 | 0.250 ± 9.088 | 0.216 | 0.257 | 0.287 | 0.0005 | 0.0020 |
Linoleic acid | c-C18:2Δ9,12 | 32.38 | 294.47 | 0.641 ± 0.576 | 0.016 | 0.743 | 0.988 | 0.720 ± 9.747 | 0.020 | 0.730 | 1.283 | 0.3740 | 0.3903 |
Linolelaidic acid | t-C18:2Δ9,12 | 31.29 | 294.47 | 0.017 ± 0.010 | 0.011 | 0.041 | 0.019 | 0.021 ± 1.009 | 0.013 | 0.020 | 0.028 | 0.2111 | 0.2413 |
Oleic acid | c-C18:1Δ9 | 30.82 | 297.49 | 26.416 ± 8.524 | 21.350 | 28.260 | 32.480 | 30.818 ± 8.451 | 28.110 | 29.720 | 31.870 | 0.0003 | 0.0014 |
Stearic acid | C18:0 | 29.79 | 298.50 | 22.679 ± 5.695 | 17.820 | 23.630 | 25.710 | 25.708 ± 6.692 | 23.420 | 24.240 | 25.580 | 0.0011 | 0.0029 |
cis -10-Heptadecanoic acid | C17:1Δ10 | 29.30 | 284.48 | 2.932 ± 1.470 | 1.874 | 2.621 | 3.898 | 3.177 ± 5.925 | 2.671 | 2.826 | 3.444 | 0.0021 | 0.0046 |
Heptadecanoic acid | C17:0 | 28.21 | 283.48 | 0.320 ± 0.094 | 0.248 | 0.321 | 0.397 | 0.375 ± 5.073 | 0.333 | 0.366 | 0.386 | 0.0448 | 0.0672 |
Palmitoleic acid | C16:1Δ9 | 27.77 | 270.45 | 0.855 ± 0.409 | 0.647 | 0.895 | 1.098 | 0.760 ± 1.489 | 0.289 | 0.722 | 1.282 | 0.1736 | 0.2193 |
Palmitic acid | C16:0 | 26.60 | 270.45 | 20.953 ± 5.023 | 17.150 | 21.220 | 23.920 | 22.929 ± 7.392 | 20.150 | 22.230 | 24.660 | 0.0036 | 0.0072 |
Pentadecanoic acid | C15:0 | 24.91 | 256.42 | 0.165 ± 0.051 | 0.133 | 0.163 | 0.199 | 0.187 ± 3.048 | 0.152 | 0.173 | 0.223 | 0.2345 | 0.2558 |