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. 2018 Oct 26;8(4):69. doi: 10.3390/metabo8040069
Fatty Acid Severe AD DLB p-Value
Name Lipid No. RT Mass Mean ± SD Q1 Median Q3 Mean ± SD Q1 Median Q3 KW FDR
Docosahexanoic Acid C22:6Δ4,7,10,13,16,19 45.01 342.51 27.694 ± 9.311 20.090 26.970 34.740 32.329 ± 9.102 26.010 31.960 36.140 0.0328 0.0525
Nervonic Acid C24:1Δ15 40.68 380.65 4.352 ± 2.385 2.747 4.633 5.775 5.348 ± 2.763 4.417 5.547 6.530 DLB 0.0251
Lignoceric Acid C24:0 39.55 382.66 0.942 ± 0.442 0.576 0.924 1.125 1.023 ± 2.384 0.846 0.990 1.243 0.0009 0.0027
cis -13,16-Docosadienoic acid C22:2Δ13,16 38.89 350.58 0.116 ± 0.059 0.084 0.102 0.140 0.144 ± 0.049 0.114 0.129 0.161 0.0014 0.0034
Arachidonic acid C20:4Δ5,8,11,14 38.08 318.49 10.83 ± 4.169 7.929 10.660 13.790 14.43 ± 5.755 12.040 14.930 16.070 0.0008 0.0027
Tricosanoic Acid C23:0 37.42 368.64 0.219 ± 0.154 0.139 0.209 0.336 0.238 ± 3.177 0.011 0.292 0.391 0.5651 0.5651
cis -11,14,17-Eicosatrienoic acid C20:3Δ11,14,17 28.93 320.51 0.684 ± 0.508 0.299 0.527 1.008 1.105 ± 7.267 0.942 1.042 1.267 0.0001 0.0006
Erucic acid C22:1Δ13 35.60 352.59 0.421 ± 0.217 0.276 0.429 0.559 0.633 ± 5.170 0.517 0.636 0.707 0.0001 0.0006
cis -8,11,14-eicosatreinoic acid C20:3Δ8,11,14 37.05 320.51 1.193 ± 0.371 0.990 1.227 1.419 1.211 ± 4.636 0.969 1.176 1.531 0.0535 0.0755
Behenic acid C22:0 35.18 354.61 0.202 ± 0.098 0.142 0.207 0.266 0.258 ± 8.088 0.213 0.255 0.325 0.0001 0.0006
cis -11,14-eicosadienoic acid C20:2 Δ11,14 35.18 308.50 0.687 ± 0.629 0.222 0.429 1.083 0.856 ± 9.508 0.435 0.859 1.369 0.2064 0.2431
Heneicosanoic acid C21:0 34.39 340.58 0.021 ± 0.008 0.015 0.021 0.026 0.023 ± 8.009 0.017 0.024 0.028 0.0312 0.0525
Linolenic acid C18:3Δ9,12,15 34.20 294.26 3.954 ± 1.650 2.722 3.979 4.928 5.195 ± 9.834 4.679 5.519 5.528 0.0001 0.0006
cis -11-Eicosanoic acid C20:1 Δ11 33.45 310.50 1.842 ± 1.316 0.377 1.975 2.640 2.137 ± 2.357 1.123 2.669 2.845 0.1439 0.1919
Arachidic acid C20:0 32.85 326.56 0.224 ± 0.079 0.169 0.239 0.266 0.250 ± 9.088 0.216 0.257 0.287 0.0005 0.0020
Linoleic acid c-C18:2Δ9,12 32.38 294.47 0.641 ± 0.576 0.016 0.743 0.988 0.720 ± 9.747 0.020 0.730 1.283 0.3740 0.3903
Linolelaidic acid t-C18:2Δ9,12 31.29 294.47 0.017 ± 0.010 0.011 0.041 0.019 0.021 ± 1.009 0.013 0.020 0.028 0.2111 0.2413
Oleic acid c-C18:1Δ9 30.82 297.49 26.416 ± 8.524 21.350 28.260 32.480 30.818 ± 8.451 28.110 29.720 31.870 0.0003 0.0014
Stearic acid C18:0 29.79 298.50 22.679 ± 5.695 17.820 23.630 25.710 25.708 ± 6.692 23.420 24.240 25.580 0.0011 0.0029
cis -10-Heptadecanoic acid C17:1Δ10 29.30 284.48 2.932 ± 1.470 1.874 2.621 3.898 3.177 ± 5.925 2.671 2.826 3.444 0.0021 0.0046
Heptadecanoic acid C17:0 28.21 283.48 0.320 ± 0.094 0.248 0.321 0.397 0.375 ± 5.073 0.333 0.366 0.386 0.0448 0.0672
Palmitoleic acid C16:1Δ9 27.77 270.45 0.855 ± 0.409 0.647 0.895 1.098 0.760 ± 1.489 0.289 0.722 1.282 0.1736 0.2193
Palmitic acid C16:0 26.60 270.45 20.953 ± 5.023 17.150 21.220 23.920 22.929 ± 7.392 20.150 22.230 24.660 0.0036 0.0072
Pentadecanoic acid C15:0 24.91 256.42 0.165 ± 0.051 0.133 0.163 0.199 0.187 ± 3.048 0.152 0.173 0.223 0.2345 0.2558