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. 2018 Nov 15;6(4):67. doi: 10.3390/toxics6040067

Table 5.

This table summarizes the exposure to Hg from Thimerosal-preserved HepB vaccines among the cases with a premature puberty diagnosis, compared to control subjects, with a reduced length of follow-up 1, within the VSD database.

Group Examined Number of Cases Diagnosed with Premature Puberty (%) Number of Controls without a Premature Puberty Diagnosis (%) Odds Ratio (95% CI) p-Value
Group I
12.5 µg Hg within 1st month 255 (52.47) 55,606 (44.79)
1.361 (1.138–1.626) <0.001
0 µg Hg within 1st month 231 (47.53) 68,539 (55.21)
Group II
25 µg Hg within first 2 months 254 (52.59) 55,615 (45.30)
1.34 (1.120–1.602) <0.01
0 µg Hg within first 2 months 229 (47.41) 67,163 (54.70)
Group III
37.5 µg Hg within first 6 months 56 (81.16) 11,786 (72.65)
1.622 (0.886–2.969) >0.10
0 µg Hg within first 6 months 13 (18.84) 4438 (27.35)

1 The controls were continuously enrolled from their date of birth for a minimum of 2.94 years (mean age of the initial premature puberty diagnosis. Hg = mercury, µg = microgram.