REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse anti myelin myelin oligodendrocyte glycoprotein (MOG, 1:1000)	Millipore	Cat#: MAB5680; RRID: AB_1587278
Chicken anti proteo-lipid-protein (PLP, 1:250)	Millipore	Cat#: Ab15454; RRID: AB_805413
Rabbit anti myelin basic protein (MBP, 1:250)	Millipore	Cat#: AB980; RRID: AB_92396
Rabbit - anti-GFP (1:1500)	Abcam	Cat#: ab6556; RRID: AB_305564
Alexa488 - Streptavidin (1:500)	Thermofisher	Cat#: S32354; RRID: AB_2336881
Alexa555 - Streptavidin (1:500)	Thermofisher	Cate#: S21381; RRID: AB_2307336
Alexa594 - Streptavidin (1:500)	Thermofisher	Cat#: S11227; RRID: AB_2313574
Chemicals, Peptides, and Recombinant Proteins
Cuprizone	Sigma-Aldrich	Cat#: C9012
Oregon Green BAPTA-1 hexapotassium salt	Thermo-Fisher	Cat#: O6806
Fura-2	Thermo-Fisher	Cat#: F1200
Biocytin	Sigma	Cat#: B4261
Tetrodotoxin (TTX) citrate	Tocris	Cat#: 1069/1
D-AP5	Tocris	Cat#: 0106/1
Carbenoxolone	Sigma-Aldrich	Cat#: C4790
Gabazine (SR-95531)	Sigma-Aldrich	Cat#: S106
Heparin	Tocris	Cat#: 2812/100
Ruthenium Red	Tocris	Cat#: 1439/100
Dantrolene	Tocris	Cat#: 0507/100
Rotenone	Tocris	Cat#: 3616/50
Cyclosporin A	Tocris	Cat#: 1101/100
Experimental Models: Organisms/Strains
Mouse: PLP-ECFP (line Q)	Frank Kirchhoff	(Battefeld et al., 2016, Hirrlinger et al., 2005)
Mouse: C57BL6/J	The Jackson Laboratory	Cat#: 000664
Oligonucleotides
FW sequencing primers for PLP-PCFQ: 5′-ATGCGTACCTGACTTTCTCCTTCT-3′	(Battefeld et al., 2016)	(Hirrlinger et al., 2005)
RV sequencing primers for PLP-PCFQ: 5′-ACTGGGTGCTCAG GTACTGGTTGT-3′	(Battefeld et al., 2016)	(Hirrlinger et al., 2005)
Software and Algorithms
NeuroPlex	RedShirt Imaging	RRID: SCR_016193
Axograph X	Axograph	RRID: SCR_014284
Graph Pad Prism	GraphPad	RRID: SCR_002798
FIJI	(Schindelin et al., 2012)	RRID: SCR_002285
Neuromantic	(Myatt et al., 2012)	RRID: SCR_013597
NEURON	(Hines and Carnevale, 2001)	RRID: SCR_005393
Maxchelator	(Schoenmakers et al., 1992)	RRID: SCR_000459
Frame splitter	This paper	https://github.com/Kolelab/Image-analysis
ΔF/F calculator	This paper	https://github.com/Kolelab/Image-analysis
Other
Vibratome	Leica	VT1200
Upright microscope	Olympus	BX61WI
Blue LED 470 nm	Thorlabs	M470L3
UV LED 340 nm	Thorlabs	M340L4
Violet LED 420 nm	Thorlabs	M420L3 (discontinued)
NeuroCCD-SMQ camera	RedShirt	N/A