Table 1.
Physicochemical properties of the nanoparticles.
| PLNPs | Zeta Potential (mV) | Hydrodynamic Size (nm) | Polydispersity Index (PDI) | Endotoxin (EU/mL) | ||
|---|---|---|---|---|---|---|
| In DW | In RPMI-1640 | In DMEM | ||||
| NH2F-PLNP | 42.1 ± 1.0 | −33.0 ± 1.3 | −34.9 ± 0.9 | 324.2 ± 4.6 | 0.3 ± 0.0 | Not detected |
| GDF-PLNP | 39.7 ± 3.6 | −29.8 ± 0.9 | −35.8 ± 1.1 | 429.6 ± 9.6 | 0.3 ± 0.0 | |
| PEGF-PLNP | 27.3 ± 1.9 | −27.2 ± 0.6 | −31.7 ± 1.0 | 280.6 ± 1.4 | 0.1 ± 0.0 | |
| ZWF-PLNP | 24.2 ± 1.5 | −30.2 ± 1.3 | −40.2 ± 1.2 | 369.1 ± 2.6 | 0.3 ± 0.0 | |
| ACF-PLNP | −17.8 ± 1.1 | −32.1 ± 1.3 | −39.9 ± 0.9 | 301.1 ± 3.5 | 0.2 ± 0.0 | |
| COOHF-PLNP | −33.4 ± 0.8 | −41.9 ± 1.5 | −46.8 ± 1.4 | 254.4 ± 0.9 | 0.0 ± 0.0 | |
| SO3F-PLNP | −40.9 ± 0.6 | −35.9 ± 1.1 | −43.3 ± 1.0 | 258.4 ± 1.4 | 0.0 ± 0.0 | |
F-PLNP—fluorophore-conjugated polystyrene nanoparticle; NH2—amine; GD—guanidium; PEG—polyethylene glycol; ZW—zwitterionic; AC—acetyl; COOH—carboxyl; SO3—sulfonic; DW—distilled water; RPMI—Roswell Park Memorial Institute; DMEM—Dulbecco’s modified Eagle medium; EU—endotoxin units.