Table 1.
A summary of the main research studies conducted on coenzyme Q10 and its reported effects on testosterone.
| Source | Dose (Mode of Treatment) | Duration | Study Population | Effect on Testosterone | Ref. |
|---|---|---|---|---|---|
| Coenzyme Q10 (Bio-Quinon Q10) | 200 mg day−1 (orally) | 21 weeks | Patients with hormonally untreated carcinoma of the prostate | (±) | [37] |
| Coenzyme Q10 (Kaneka, Osaka, Japan) | 300 mg day−1 (orally) | 26 weeks | Infertile men | (±) | [38] |
| Coenzyme Q10 (Nutri Q10, Nutri Century, Toronto, ON, Canada) | 900 mg day−1 (orally) | 12 months | Infertile men with idiopathic oligoasthenoteratozoospermia | (±) | [39] |
| Coenzyme Q10 | Therapeutic dose (orally) | 3 and 6 months | Patients with idiopathic oligoasthenospermia | (±) | [40] |
| Coenzyme Q10 (Nature Made Pharmaceutical Company, Mission Hills, CA, USA) | 200 mg day−1 (orally) | 8 weeks | Patients with polycystic ovary syndrome | (−) | [41] |
| Coenzyme Q10 (Nutralife Co., Richmond Hill, Canada) | 125, 250, and 500 mg kg−1 day−1 (orally) | 96 days | Bilateral orchidectomized male mice | (±) | [42] |
| Coenzyme Q10 (Nutralife Co.) | 125 and 250 mg kg−1 day−1 (orally) | 96 days | Gonadectomized male mice | (−) | [43] |
| Coenzyme Q10 | 10 and 20 mg kg−1 day−1 (orally) | 2 months | Male ostriches | (±) | [44] |
| Coenzyme Q10 (Sigma Chemical Company, St. Louis, MO, USA) | 10 mg kg−1 day−1 (intraperitoneally) | 5 days | Male rats with sodium arsenite-induced reproductive toxicity | (+) | [45] |
| Coenzyme Q10 | 10 mg kg−1 day−1 (orally) | 20 days | Male rats with isoproterenol-induced reproductive toxicity | (+) | [46] |
| Coenzyme Q10 (Arab Co. for Pharmaceuticals & Medicinal Plants, Cairo, Egypt) | 10 mg kg−1 day−1 (orally) | 10 weeks | Male rats with aluminum chloride-induced reproductive toxicity | (+) | [47] |
(+) Increase; (−) Decrease; (±) No effect.