Table 2.
Lung histopathological changes from before and after CPB.
| Lung Tissue | Groups | Before | After | Before vs. After | Time-Group | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | Min | Max | Mean | Min | Max | p-Value | p-Value | ||
| Alveolar congestion | Control | 1.1 | 1 | 2 | 1.2 | 1 | 2 | 0.06 * | 0.62 |
| HTK | 1.0 | 1 | 1 | 1.3 | 1 | 2 | |||
| O2 | 1.1 | 1 | 2 | 1.3 | 1 | 2 | |||
| Heamorhage | Control | 0.4 | 0 | 2 | 0.4 | 0 | 2 | 0.72 | 0.64 |
| HTK | 0.1 | 0 | 1 | 0.3 | 0 | 1 | |||
| O2 | 0.2 | 0 | 1 | 0.2 | 0 | 1 | |||
| Neutrophilic infiltration | Control | 1.1 | 1 | 2 | 1.6 | 1 | 2 | <0.001 | 0.32 |
| HTK | 1.1 | 1 | 2 | 1.5 | 1 | 2 | |||
| O2 | 1.2 | 1 | 2 | 1.3 | 1 | 2 | |||
| Thickness of alveolar wall hyaline membranes | Control | 1.4 | 1 | 3 | 1.6 | 1 | 3 | 0.01 * | 0.58 |
| HTK | 1.6 | 1 | 3 | 2.1 | 1 | 3 | |||
| O2 | 1.5 | 1 | 3 | 1.6 | 1 | 3 | |||
| Total score | Control | 4.1 | 3 | 6 | 4.6 | 3 | 7 | 0.001 | 0.36 |
| HTK | 3.7 | 3 | 5 | 5.1 | 3 | 7 | |||
| O2 | 3.9 | 3 | 7 | 4.3 | 3 | 7 | |||
Pair t-test or its corresponding non-parametric test (*) was used to identified differences between paired samples (Before vs. After CPB) and factorial two-way ANOVA to detect differences between patients as a consequence of surgery and treatment received (Time-Group interaction). A p-value < 0.05 was considered significant. Data is presented as means, minimum (min) and maximum (max) values.