Figure 2.

Overview of various socioeconomic and biological factors contributing to disparity in TNBC progression in African American (AA) versus European American (EA) women. Various socioeconomic factors such as low income and poor access to health care can aid in high prevalence of obesity. Obese state can modify various signaling pathways and directly impact various tumor-promoting biological process including growth, invasion, and migration. These socioeconomic and biological factors contribute to TNBC progression in AA women directly or indirectly.