Table 5.
Pre and post study associations between essential fatty acid concentrations (LA, ALA), rs174548 genotype, total saturated fatty acid concentration and DHA intake (post intervention only), and major n-3 and n-6 long chain polyunsaturated fatty acid concentrations; only significant (p < 0.01) standardized β-coefficients are given (n = 82).
| R2 | β DHA Intake |
p-Value | β LA | p-Value | β ALA | p-Value | β rs174548 | p-Value | β Total Saturated Fatty Acids | p-Value | β rs174548 × Precursor | p-Value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| pre | |||||||||||||
| DGLA | 0.69 | −0.22 | 4.1 × 10−3 | 0.30 | 1.0 × 10−6 | 0.86 | 1.1 × 10−18 | −0.17 | 4.0 × 10−3 | ||||
| ARA | 0.57 | −0.44 | 3.3 × 10−9 | 0.53 | 1.1 × 10−7 | ||||||||
| DPA n-6 | 0.36 | −0.51 | 2.5 × 10−7 | 0.66 | 7.2 × 10−8 | ||||||||
| EPA | 0.84 | −0.33 | 7.6 × 10−9 | 0.83 | 3.5 × 10−30 | −0.18 | 2.3 × 10−5 | 0.44 | 4.8 × 10−12 | −0.28 | 7.8 × 10−9 | ||
| DPA n-3 | 0.69 | −0.21 | 5.6 × 10−3 | 0.61 | 5.2 × 10−14 | −0.24 | 7.8 × 10−5 | 0.59 | 1.8 × 10−9 | −0.18 | 5.3 × 10−3 | ||
| DHA | 0.60 | 0.65 | 9.5 × 10−13 | −0.28 | 4.9 × 10−5 | 0.36 | 1.2 × 10−4 | −0.23 | 1.4 × 10−3 | ||||
| post | |||||||||||||
| DGLA | 0.61 | −0.23 | 8.5 × 10−3 | −0.21 | 3.9 × 10−3 | 0.44 | 3.6 × 10−8 | 0.87 | 1.6 × 10−17 | ||||
| ARA | 0.43 | −0.39 | 2.7 × 10−5 | 0.52 | 1.0 × 10−6 | ||||||||
| DPA n-6 | 0.47 | −0.39 | 3.9 × 10−6 | −0.52 | 1.7 × 10−8 | 0.68 | 1.9 × 10−10 | ||||||
| EPA | 0.90 | −0.20 | 4.8 × 10−6 | 0.80 | 1.0 × 10−36 | −0.20 | 3.2 × 10−7 | 0.27 | 3.3 × 10−8 | −0.18 | 6.7 × 10−7 | ||
| DPA n-3 | 0.69 | 0.55 | 7.0 × 10−13 | −0.21 | 1.7 × 10−3 | 0.41 | 2.4 × 10−7 | −0.16 | 9.5 × 10−3 | ||||
| DHA | 0.51 | 0.54 | 2.3 × 10−10 | 0.30 | 4.0 × 10−4 | 0.30 | 1.3 × 10−3 |