Table 1.
Clinical profiles of 267 patients with chronic liver diseases enrolled in this study. F/M: Female/Male; ns: not significant; HCV/HBV/alcohol/NASH/AIH+PBC: hepatitis C virus/hepatitis B virus/alcohol/nonalcoholic steatohepatitis/autoimmune hepatitis + primary biliary cholangitis.
| Zn Group | No Treatment Group | p-Value | |
|---|---|---|---|
| number of patients | 196 | 71 | |
| mean age (years) | 73.2 ± 9.5 | 66.4 ± 12.6 | p < 0.0001 |
| gender (F/M) | 97/99 | 36/35 | ns |
| chronic hepatitis/liver cirrhosis | 93/103 | 56/15 | p < 0.0001 |
| Child-Pugh (A/B/C) | 98/89/9 | 67/4/0 | p < 0.0001 |
| Zn (μg/dL) | 51.0 ± 16.8 | 61.7 ± 9.1 | p < 0.0001 |
| T-Bil (mg/dL) | 1.2 ± 1.8 | 0.8 ± 0.4 | p < 0.0001 |
| albumin (g/dL) | 3.5 ± 0.6 | 4.0 ± 0.3 | p < 0.0001 |
| PT activity (%) | 77.8 ± 17.6 | 89.1 ± 11.7 | p < 0.0001 |
| platlet count (104/L) | 12.9 ± 14.2 | 15.8 ± 7.1 | p = 0.035 |
| observation period (Months) | 40.0 ± 31.5 | 39.6 ± 22.8 | ns |
| Etiology (HCV/HBV/alcohol/NASH/AIH+PBC) | 121/10/23/19/23 | 35/13/7/7/8 | ns |