Table 6.
Frequencies of the haplotypes of VKORC1 and CYP2C9 genes among the 212 warfarin responsiveness patients.
| Gene | Haplotypes | Frequency * (%) | Odds Ratio (95% CI) | p-Value ** |
|---|---|---|---|---|
| VKORC1 | TGAG | 0.512 | 0.00 | ------ |
| CCGG | 0.326 | −0.18 (−0.33–−0.03) | 0.02 | |
| CCGA | 0.129 | −0.08 (−0.28–0.12) | 0.46 | |
| CGGG | 0.026 | −0.05 (−0.47–0.36) | 0.8 | |
| TCGG | 0.007 | 0.55 (−0.22–1.32) | 0.16 | |
| CYP2C9 | CAC | 0.767 | 0.00 | ------ |
| TAT | 0.115 | 0.25 (0.04–0.45) | 0.018 | |
| TCC | 0.094 | 0.06 (−0.17–0.3) | 0.59 | |
| TAC | 0.021 | 0.44 (−0.01–0.89) | 0.059 | |
| TCT | 0.003 | 0.4 (−0.9–1.71) | 0.55 |
* Genetic haplotype frequency of 212 warfarin intake patients, ** p-value < 0.05 is considered significant.