Figure 13.

Proliferation of the smooth endoplasmic reticulum associated with microsomal induction of gamma-glutamyltransferase (GGT) due to alcohol abuse. Chronic alcohol consumption induces also various other microsomal functions, which are of potential clinical relevance. In addition, increased GGT activities of the plasma membranes may contribute to increases in the serum [296,297]. Symbol: ?, under discussion. The original figure was published in an earlier report [23] and is reproduced with the permission of the Publisher Wiley (Hoboken, NJ, USA).