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. 2018 Dec 8;10(12):698. doi: 10.3390/v10120698

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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An amino acid sequence alignment of ZIKV prM proteins. Strains are shown by accession number, geographic location, and year of isolation. Identity of the strain H/PF/2013 from the Asian genotype (accession number KJ776791) is shown by a dash. Sequence position relative to the prM protein of that strain is shown on the top of the figure. Predicted coiled regions of the protein are indicated by a blue arrow on top of the alignment. Predicted exposed residues are indicated by an asterisk on the upper part of the alignment. Positions where amino acid substitutions were found between pre-epidemic and epidemic strains are highlighted in green. Position 139 is shown in red.