Table 4.
Correlation coefficients (r) between serum free concentration of PBUTs and parameters of cardiac function, structure, and exercise capacity.
Study Parameters | IXS | PCS | PCG | IAA | HA |
---|---|---|---|---|---|
CPOmax | −0.48 ** | −0.51 ** | −0.52 ** | −0.40 ** | −0.29 * |
Peak Qt | −0.41 ** | −0.44 ** | −0.45 ** | −0.33 * | −0.40 ** |
Peak MAP | −0.29 * | −0.29 * | |||
Peak HR | −0.41 ** | −0.31 * | |||
VO2max | −0.41 ** | −0.48 ** | −0.42 ** | −0.41 ** | −0.38 ** |
Peak C(a-v)O2 | −0.332 * | −0.31 * | |||
LVMI | |||||
IVSd | 0.33 * | 0.32 * |
Heat map showing negative correlations in and positive correlations in
. Blank spaces represent no significant correlation. ** p < 0.01 and * p < 0.05 on Pearson correlation. Log-transformed values of serum concentrations of uremic toxins were used for analysis. CPOmax: peak cardiac power; peak Qt: peak cardiac output; MAP: mean arterial pressure; peak HR: peak heart rate; VO2max: aerobic exercise capacity; C(a-v)O2: arteriovenous O2 difference; LVMI: left ventricular mass index; IVSd: interventricular septal thickness at end diastole. Indoxyl sulfate (IXS), p-cresyl sulfate (PCS), p-cresyl glucuronide (PCG), indole acetic acid (IAA), and hippuric acid (HA).