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. 2018 Dec 5;10(12):520. doi: 10.3390/toxins10120520

Table 4.

Correlation coefficients (r) between serum free concentration of PBUTs and parameters of cardiac function, structure, and exercise capacity.

Study Parameters IXS PCS PCG IAA HA
CPOmax −0.48 ** −0.51 ** −0.52 ** −0.40 ** −0.29 *
Peak Qt −0.41 ** −0.44 ** −0.45 ** −0.33 * −0.40 **
Peak MAP −0.29 * −0.29 *
Peak HR −0.41 ** −0.31 *
VO2max −0.41 ** −0.48 ** −0.42 ** −0.41 ** −0.38 **
Peak C(a-v)O2 −0.332 * −0.31 *
LVMI
IVSd 0.33 * 0.32 *

Heat map showing negative correlations in Inline graphic and positive correlations in Inline graphic. Blank spaces represent no significant correlation. ** p < 0.01 and * p < 0.05 on Pearson correlation. Log-transformed values of serum concentrations of uremic toxins were used for analysis. CPOmax: peak cardiac power; peak Qt: peak cardiac output; MAP: mean arterial pressure; peak HR: peak heart rate; VO2max: aerobic exercise capacity; C(a-v)O2: arteriovenous O2 difference; LVMI: left ventricular mass index; IVSd: interventricular septal thickness at end diastole. Indoxyl sulfate (IXS), p-cresyl sulfate (PCS), p-cresyl glucuronide (PCG), indole acetic acid (IAA), and hippuric acid (HA).