Table 3.
Interaction between BP and HbA1c groups by n-6 fatty acid intake.
| n-6 Fatty Acid | HbA1c Level | Hypertension | Normal BP | p Value for Interaction |
|---|---|---|---|---|
| Average (SD) | Average (SD) | |||
| n-6 fatty acid (g/1000 kcal) | Normal | 5.12 (1.31) | 5.59 (1.33) | 0.035 |
| High | 5.11 (1.10) | 4.54 (1.22) | ||
| LA (g/1000 kcal) | Normal | 4.96 (1.43) | 5.42 (1.31) | 0.033 |
| High | 4.94 (1.09) | 4.37 (1.21) | ||
| GLA (mg/1000 kcal) | Normal | 3.87 (2.41) | 4.21 (3.00) | 0.682 |
| High | 4.78 (2.25) | 5.50 (2.52) | ||
| EA (mg/1000 kcal) | Normal | 23.6 (8.74) | 25.6 (8.43) | 0.949 |
| High | 24.7 (6.95) | 26.9 (6.90) | ||
| DGLA (mg/1000 kcal) | Normal | 15.3 (5.22) | 16.6 (4.94) | 0.585 |
| High | 16.3 (5.27) | 16.6 (3.57) | ||
| AA (mg/1000 kcal) | Normal | 89.9 (31.5) | 95.4 (29.3) | 0.629 |
| High | 96.6 (34.9) | 96.9 (27.5) | ||
| DPA (mg/1000 kcal) | Normal | 5.30 (3.14) | 5.05 (3.33) | 0.147 |
| High | 5.87 (3.82) | 7.29 (2.82) |
p values from a two-way analysis of variance means interaction between HbA1c groups and BP groups. Hypertensive subjects were defined as participants with a greater SBP than 140 mmHg, a DBP greater than 90 mmHg, or the use of antihypertensive medication. A high HbA1c level was defined as an HbA1c value of 6.5% or higher. Forty-one participants had a high HbA1c level; 12 high HbA1c level participants had a normal BP, and 29 had hypertension. There were 592 participants with a normal HbAc1 level; 271 had a normal BP, and 321 had hypertension. Abbreviations: BP, blood pressure; HbA1c, hemoglobin A1c; LA, linoleic acid; GLA. Gamma-linolenic acid; EA, eicosadienoic acid; DGLA, dihomo-gamma-linolenic acid; AA, arachidonic acid; and DPA, docosapentaenoic acid.