HH	Hedgehog-GLI
SMO	Smoothened
BCC	Basal cell carcinoma
MB	Medulloblastoma
PNET	Primitive neuroectodermal tumors
AML	Acute myeloid leukemia
SHH	Sonic hedgehog
IHH	Indian hedgehog
DHH	Desert hedgehog
PTCH1	Patched 1
GPCR	G-protein-coupled receptor
SUFU	Suppressor of Fused
KIF7	Kinesin family member 7
PC	Primary cilium
PKA	Protein kinase A
CK1	Casein kinase 1
GSK3β	Glycogen synthase kinase 3β
HHIP1	Hedgehog-interacting protein
TNF-α	Tumor necrosis factor-α
mTOR	Mammalian target of rapamycin
S6K1	S6 kinase 1
ECD	Extracellular domain
CRD	Cysteine-rich domain
TMD	Transmembrane domain
ICL	Intracellular loop
ECL	Extracellular loop
Gprk2	G protein-coupled receptor kinase 2
PI4P	Phosphatidylinositol 4-phosphate
Cul4	Cullin4
DDB1	DNA damage binding protein 1
DBP	Drug-binding pocket
FDA	Food and Drug Administration
Pgp	P-glycoprotein
ATO	Arsenic trioxide
IGFR	Insulin growth factor receptor
PTEN	Phosphatase and tensin homolog
PI3K	Phosphatidylinositol-4,5-bisphosphate 3-kinase
EGFR	Epidermal growth factor receptor
PDGFR	Platelet-derived growth factor receptor
MAPK	Mitogen-Activated Protein kinase
ERK	Extracellular Signal-Regulated Kinase
aPKCι/λ	Atypical protein kinase Cι/λ
DYRK	Dual specificity tyrosine-phosphorylation-regulated kinase
HDAC	Histone deacetylase
BET	Bromo- and extra-terminal domain
SRF	Serum response factor
MLK1	Megakaryoblastic leukemia 1