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. 2018 Dec 7;10(12):497. doi: 10.3390/cancers10120497

Table 4.

Spine SBRT Cohorts.

Study (Year) No. of Patients Dose/No. of Fractions(#) Local Control Pain Control ≥Grade 3 Toxicities
Chang et al. 2009 [66] 129 16–39 Gy/1–5# 69% at 3 years 91% No toxicity
Schipani et al. 2011 [67] 124 18 Gy/1# 92% at 3 years 92% No toxicity
Wang et al. 2012 [68] 149 27–30 Gy/3# 72% at 2 years 86% Acute 9% (pain, GI, fatigue)
Guckenburger et al. 2014 [69] 301 Median 24 Gy/3# 84% at 2 years Not reported Acute 0.01% (pain)
Bishop et al. 2015 [70] 285 18–27 Gy/1–3# 82% at 3 years Not reported Not reported
Bernard et al. 2017 [71] 127 Median 27 Gy/3# 76% at 2 years Not reported 6.75% Spine fracture