Table 5.
Top highly and selectively expressed circRNAs for α-, β-, and exocrine cells. The averaged log-transformed junction read counts (log2(RC) are shown as a measure of normalized expression for each circRNA. Other columns include the total number of exons for each circRNA as represented by exon Count, circRNA length, and host gene name and biotype.
| Gene Name | circ ID | Exon Count | circRNA Length | log2(RC) | Gene Biotype |
|---|---|---|---|---|---|
| α-cell selective circRNAs | |||||
| PLCE1 | 10:94030682:94032252 | 1 | 1570 | 4.43 | protein_coding |
| FAP | 2:162183413:162203145 | 9 | 822 | 3.38 | protein_coding |
| KANK1 | 9:710803:713464 | 1 | 2661 | 3.27 | protein_coding |
| MCU | 10:72715110:72715902 | 2 | 165 | 3.02 | protein_coding |
| C1orf168 | 1:56787174:56792803 | 3 | 944 | 2.95 | protein_coding |
| FRMPD3 | X:107526581:107533550 | 3 | 304 | 2.93 | protein_coding |
| PLCE1 | 10:94245945:94246621 | 1 | 676 | 2.88 | protein_coding |
| KIAA1217 | 10:24219625:24219909 | 1 | 284 | 2.70 | protein_coding |
| SYTL5 | X:38033533:38034008 | 1 | 475 | 2.70 | protein_coding |
| FAM126A | 7:22960255:22991139 | 9 | 1019 | 2.64 | protein_coding |
| SPG21 | 15:64974601:64983593 | 4 | 476 | 2.55 | protein_coding |
| POU6F2 | 7:39204234:39207620 | 2 | 321 | 2.55 | protein_coding |
| PITPNB | 22:27894554:27914347 | 6 | 436 | 2.52 | protein_coding |
| PRKCE | 2:46001403:46010517 | 4 | 614 | 2.49 | protein_coding |
| SPATS2L | 2:200329430:200419496 | 5 | 517 | 2.49 | protein_coding |
| β-cell selective circRNAs | |||||
| SNORA14A | 7:75943781:75943916 | 1 | 135 | 4.96 | snoRNA |
| PDE4B | 1:65913244:65918835 | 2 | 351 | 4.37 | protein_coding |
| TNFRSF11A | 18:62348167:62349937 | 2 | 208 | 4.21 | protein_coding |
| NRG1 | 8:32595827:32616885 | 4 | 402 | 3.95 | protein_coding |
| SNORD9 | 14:21392149:21392253 | 1 | 104 | 3.63 | snoRNA |
| DGKB | 7:14574211:14673027 | 8 | 738 | 3.58 | protein_coding |
| GTDC1 | 2:144208602:144211579 | 2 | 267 | 3.48 | protein_coding |
| SYNE2 | 14:63998913:64022863 | 12 | 2284 | 3.39 | protein_coding |
| HDAC9 | 7:18666212:18666476 | 1 | 264 | 3.36 | protein_coding |
| TNRC6B | 22:40117054:40156182 | 3 | 233 | 3.36 | protein_coding |
| TGFBR3 | 1:91861470:91861644 | 1 | 174 | 3.29 | protein_coding |
| NRD1 | 1:51827795:51834170 | 2 | 228 | 3.29 | protein_coding |
| GLCCI1 | 7:8003907:8060248 | 4 | 509 | 3.21 | protein_coding |
| ROR1 | 1:64009304:64050716 | 3 | 391 | 3.04 | protein_coding |
| TSNAX | 1:231537212:231542611 | 2 | 246 | 2.88 | protein_coding |
| Exocrine-cell selective circRNAs | |||||
| SNORD26 | 11:62855291:62855366 | 1 | 75 | 5.82 | snoRNA |
| PNLIPRP2 | 10:116625945:116627874 | 3 | 373 | 4.78 | polymorphic_pseudogene |
| CFTR | 7:117504252:117559655 | 10 | 1531 | 4.29 | protein_coding |
| C15orf38-AP3S2 | 15:89903215:89910819 | 4 | 580 | 4.29 | protein_coding |
| PNLIPRP2 | 10:116625945:116631357 | 5 | 613 | 4.21 | polymorphic_pseudogene |
| RAB3D | 19:11335446:11335783 | 2 | 244 | 4.13 | protein_coding |
| SEL1L | 14:81492479:81495137 | 2 | 126 | 3.81 | protein_coding |
| TRHDE | 12:72562164:72575542 | 5 | 533 | 3.64 | protein_coding |
| TRHDE | 12:72562852:72575542 | 4 | 467 | 3.52 | protein_coding |
| SLC7A6 | 16:68266592:68266721 | 1 | 129 | 3.09 | protein_coding |
| IKBKB | 8:42325969:42329214 | 2 | 219 | 3.09 | protein_coding |
| SLC43A1 | 11:57491223:57491862 | 3 | 322 | 3.09 | protein_coding |
| C3orf52 | 3:112109542:112113145 | 2 | 253 | 2.91 | protein_coding |
| ARF4 | 3:57583897:57584464 | 2 | 191 | 2.91 | protein_coding |
| SNORD58B | 18:49491663:49491729 | 1 | 66 | 2.91 | snoRNA |